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Residues in or on treated products, food and feed
The matrices intended for human consumption, i.e. food and drink or raw agricultural commodities, may show the evidence that substances like Plant Protection Products were used to treat the crops or to preserve the products during the storage, this sign is defined as being a Residue. Animal products, for example milk, may contain residues due to the treated crops used for animal feeding. Moreover, animal tissues entering the human food chain can retain residues of Veterinary Drugs.
BioTecnologie BT has a long track record for the performance of residue field studies and the laboratory experts conduct routinely the set-up/optimization, the validation of mono and multi-residue analytical methods with leading edge analytical equipment:
LC MS/MS, UPLC MS/MS, LC DAD UV-VIS/Fluorescence, ICP MS, GC MS, GC MS/MS, GC FID/µECD
OECD TG 509 Crop Field Trials (CTF)
CTF are conducted to quantify the expected range of residues in or on raw agricultural commodities (RACs), including feed items following the treatment according to the proposed or set Good Agricultural Pratice. They should be designed to reflect pesticide use patterns that lead to the highest possible residues, to determine (where relevant) the rate of residues decline on commodities of interest and to define residue values for conducting dietary risk assessment and to set Maximum Residue Levels.
OECD TG 508 Magnitude of the Pesticide Residues in Processed Commodities
These studies are carried out to determine the transfer of residues from a RAC to its different processed commodities resulting from the transformation undergone: juice, purée, jam, canned fruits and berries, young and bottled wine, raisins, refined and raw oil, waste water, polished rice flour, bran and bread and many others.
OECD TG 504 Residues in Rotational Crops (Limited Field Studies)
Limited Field Studies aimed to determine the amount of pesticide residues which may be accumulated into rotational crops via soil uptake following realistic agricultural practice.
Residues in environmental samples
Based on the results from toxicological and ecotoxicological tests, residue definition for monitoring purposes
should cover the components which are part of the residue definition for the evaluation of risks considered to be relevant during the assessment of such results. Should be submitted post-registration monitoring data on fate and behaviour of the active substance, its metabolites, reaction and degradation products in:
Soil, Surface water, Ground water, Drinking water, Sediments and Air and/or in Animal tissues
Determination of the exposure concentrations of the organisms in the ecotoxicological tests
The increasing requirements of the testing guidelines to verify the concentrations at which no target organisms are exposed during the tests, as example the feeding solution in honeybees studies, or the "old" requirements as the analyses of exposure concentrations in the media during the aquatic tests has led the staff to specialize in these kind of matrices.